The number of children referred for medical care for issues relating to gender identity and dysphoria has increased rapidly in recent years, particularly among teenage girls. There are different interpretations and views in clinical practice as to how the evidence on using hormone treatments during puberty should be reflected in care, with concerns relating to safety and long-term effects, the affirmative approach to diagnosis for gender identity issues, and patient capacity and autonomy. This POSTnote will summarise the latest research on the impacts of hormone treatments, with a focus on clinical outcomes, and highlighting uncertainties in the evidence base.

Work on this briefing will commence in November 2022.

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