Documents to download

Biological ageing results from the accumulation of damage within cells, leading to a loss of function and, ultimately, cell death.  The underlying mechanisms of ageing are also risk factors in the onset of frailty, disability and long-term disease. This POSTnote examines the biological basis of ageing, the potential to manipulate the ageing process and to use such knowledge to promote better health later in life.

Acknowledgements

POSTnotes are based on literature reviews and interviews with
a range of stakeholders and are externally peer reviewed.
POST would like to thank interviewees and peer reviewers
for kindly giving up their time during the preparation

Dr Aoife Kidy (Alzheimer’s Society)
Dr Mathew Norton (Alzheimer’s Research UK)
Professor Wolf Reik (Babraham Institute)
Dr Jon Houseley (Babraham Institute)
Dame Linda Partridge (University College London)
Professor Lynne Cox (University of Oxford)
Catherine Joynson (Nuffield Council of Bioethics)
Professor Diana Kuh (University College London)
Professor Martin Knapp (London School of Economics)
Professor Mark Hanson (University of Southampton)
Gareth Giles (University of Southampton)
Dr Chandni Jacobs (University of Southampton)
Professor Thomas Von Zglinicki (Newcastle University)
Professor John Mathers (Newcastle University)
Professor Thomas Kirkwood (Newcastle University)
Dr João Pedro de Magalhães (Univesity of Liverpool)
Dr Alison Tedstone (Public Health England)


Documents to download

Related posts

  • A POSTnote on preventing zoonotic diseases will review the evidence on a One Health approach to zoonoses prevention. It will focus on the animal-environment-human interface in both wild and domestic animals, reviewing national and international policy approaches, and lessons learnt from previous epidemics. It will also summarise opportunities and challenges for the UK’s role in global health and biosecurity policy arenas post COVID-19. Provisional start date: January 2021.

  • A POSTnote on childhood obesity will summarise the latest trends in children’s diet, obesity and related health conditions and review the impacts of previous policy changes such as the tax on sugar sweetened drinks. It will also examine the factors underlying the growing gap in outcomes for children from the most and least deprived backgrounds. Provisional start date: January 2021.

  • Evolving life sciences and agricultural research approaches may have a decreasing need to access physical resources in future, such as plant seeds or viral material. Information and genetic data may be all that is required for commercial exploitation of biological resources. This POSTnote summarises the challenge this creates for international discussions on the governance of genetic resources and the possible options for addressing these.