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Research into sequencing the human genome holds out the promise of better understanding, diagnosis and treatment of a wide range of

hereditary diseases. Cystic Fibrosis (CF) is the most common such disease among Caucasians in the UK, and also the best-characterised example of a condition caused by the mutation of a single gene. This briefing summarises recent developments in understanding, diagnosis and treatment of CF, and examines the issues that arise.

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