COVID-19 therapies

This article was updated on 1 May and again on 6 July. Since its original publication on 17 April, the number of COVID-19 clinical trials has increased from 524 to 2,378. There is no cure for COVID-19. Researchers are testing existing drugs to see if they act against SARS-CoV-2 or alleviate the symptoms of the disease. New drugs are also in development, but this is at a very early stage. Results from trials on existing drugs have already been reported with some positive findings. Dexamethasone i…

Read more

COVID-19: July update on face masks and face coverings for the general public

There is some weak evidence that face masks and coverings can reduce transmission of the virus in some specific circumstances, particularly poorly ventilated and crowded indoor spaces. Policy on using face coverings differs across the UK. They are recommended across the UK in circumstances where social distancing is difficult. In Scotland they must be used on public transport and from 10 July they will be mandatory in shops. In England they are mandatory on public transport and in NHS hospitals…

Read more

COVID-19 and social distancing: the 2 metre advice

An infected person produces respiratory droplets when talking, coughing and sneezing. These are responsible for the transmission of virus between people. Droplets can travel up to 2m, with finer aerosols containing smaller viral particles travelling even further. Numerous complex and interacting factors influence how they move and settle onto surfaces, and how infectious they are. The further away a person is, the fewer droplets they will be exposed to and so their risk of being infected with th…

Read more

Antibody tests for COVID-19

There is insufficient scientific evidence to know whether the presence of SARS-CoV-2 antibodies confers protection from subsequent infections, and if so at what level. Antibodies are only one part of the immune response to infection. Tests that detect SARS-CoV-2 antibodies are available. They can determine whether someone has had COVID-19. Tests can reveal those who are unaware that they had COVID-19 because they had mild or no symptoms. Test samples must be analysed in a laboratory – no home…

Read more

Immunity to COVID-19

Scientific understanding of the immune response to COVID-19 is incomplete but numerous research studies are underway. There is little evidence to suggest that exposure to other coronaviruses can confer protection against SARS-CoV-2. There is very good evidence that it takes at least 14 days to develop an antibody response to SARS-CoV-2. A significant proportion of people exposed to SARS-CoV-2 make very little or no detectable antibodies at all. There is insufficient scientific evidence to know w…

Read more

COVID-19 in children

There is very good evidence that children who have COVID-19 are much less likely to develop severe symptoms and much less likely to die from the disease than people in older age groups. There is good evidence that children under 13 years old are less susceptible to developing clinical disease (this means having recognisable signs and symptoms) than adults. It is not yet clear whether this is also the case for older children. There is some research indicating that children aged 13 years and under…

Read more

COVID-19 and international approaches to exiting lockdown

The UK Government announced its approach to exiting lockdown on 10 May in a statement by the Prime Minister and in a report published on 11 May. Current models suggest that 5.38% of the UK population has been infected with COVID-19. To lift restrictions the World Health Organisation has outlined key criteria that should guide decision making, such as ensuring that health systems can identify, isolate, test, trace contacts and quarantine COVID-19 cases. Several countries have eased measures with…

Read more

Face masks, face coverings and COVID-19

This article goes over the types of masks that exist. It explores how effective are they at preventing transmission of coronavirus, according to the latest research. It reviews the advice on masks and face coverings from public health organisations, and presents official guidance from several nations. This is part of our rapid response content on COVID-19. You can view all our reporting on this topic under COVID-19. …

Read more

Research for Parliament: Preparing for a changing world

This document builds on POST's previous publication, Topics of Interest 2018 (POSTbrief 27). The subjects are listed under under six category headings based on the drivers of change identified in POSTnote 500: demographic change and healthcare; social and cultural trends; geopolitical and governance challenges; environmental pressures and climate change; resource security and sustainability; and technological advance.…

Read more

Shift Work, Sleep and Health

A POSTnote that describes how working outside of daytime hours – shift work – affects physical and mental health and performance through its impact on sleep and circadian timing. It highlights the latest research, explains the implications for policy and how research can inform the design of interventions to improve shift workers' sleep and overall health.…

Read more